PHARMACOLOGY
RESPIRATORY SYSTEM
Drug used in treat of cough
Definition:-
Cough is a protective reflex, intended to remove irritants and accumulated secretions from the respiratory passages. It is the common symptom of airway diseases.
Cough reflex arc:-
Coughing may be triggered by mechanical or chemical stimulation of throat, respiratory passages or stretch receptors in lungs.
Causes of cough:-
Infection
Allergy
Gastro esophageal reflex disease
Pleural disease
Drug induced Cough
Malignancy
Types of cough:-
Based on secretion:-
- Productive
- Non productive
Based on duration:-
- Acute
- Subacute
- chronic
Productive cough:-
Helps to clear the airway. Suppression of productive cough is harmful, as it may lead to infections.
Non - productive cough:-
It should be suppressed.
Drugs used in treatment of cough:-
1. Antitussives:-
Codeine
Pholcodine
Noscapine
Dextromethorphan
Antihistamines
Chlophedianol
2. Pharyngeal demulcents:-
Lozenges
Linctuses
Liquorice
3. Expectorants:-
Sodium and potassium citrate
Potassium iodide
Guaiphenesin
Ammonium chloride
4. Mucolytics:-
Bromhexine
Acetylcysteine
Carbocisteine
Ambroxol


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